Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
One such development is 60 Water Street in Dumbo, a 290-unit rental with a 24-hour concierge and a roof deck offering Manhattan views. Leasing begins next month, with rent for a two-bedroom starting at a jaw-dropping $6,018 a month. “People want that condo-like living, even though they’re renting and not owning,” said Jodi Ann Stasse, the managing director of new developments for Citi Habitats.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Song “Friends Forever” (Yang Kun and Zhang Liangying)
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Wishing you all the blessings of a beautiful New Year season.
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Canadians: I'm afraid that while you are here you will be repeatedly mistaken for Americans and blamed for all sorts of stuff you had nothing to do with. Unless you can think of a quick and simple way to distinguish yourselves at a glance – flower in lapel? Saddle shoes? Maple leaf eyepatch? – then you are just going to have to suck it up.
The relocation is also part of the integration plan for the Beijing-Tianjin-Hebei cluster, which aims to ease congestion in the capital and achieve more balanced development in the region.
These countries performed the best overall in the 2017 Best Countries rankings. The rankings aim to gauge global perceptions of the world’s biggest economies.
Trends and targets in antiviral phototherapy
Industrial production rose 6.1 per cent year on year in October, according to China’s National Bureau of Statistics, unchanged from September’s level and just below a median forecast from economists of 6.2 per cent.
Economists had forecast a 1.5 per cent annual rate, after a 1.6 per cent reading in September. Beijing's inflation target is "around 3 per cent" this year.
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
补救办法： 做预算。 如果你不能估算需要多少钱才能过上令你感到舒适的生活，你就无法确切地知道为了1万美元薪水而换工作是否真的划算。在比较新、旧工作时，列出各自的优缺点，这会对你很有帮助。如果新工作只是薪水更高一点，那么你可以比较下这个工作是否要求更长的工作时间和完成更多的工作任务。请记住，调查表明：年收入在7.5万美元以内，幸福感会随着薪水的增加而增加，但是一旦薪水超过这个水平，幸福感的增加便不再明显。因此，如果你认为薪水增加到8.5万或9万美元会使你更加快乐，这时你或许应该着手解决生活中那些与金钱无关而引起的不快乐。
Diagnostic technologies for COVID-19: a review
While the president emerged as the narrow winner on the night, the encounter, which was cordial and largely uneventful compared with the previous two debates, is unlikely to have much impact on the outcome of the election.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
In the original casting, Michael Keaton was set to play the character. However, ABC executives begged the writers and producers to keep Jack alive. They believed the character was too likeable to die off so quickly. The writers agreed. Michael Keaton was not interested in signing up for a long-running show. Instead, the role of Jack was given to Matthew Fox. The rest is TV history.
By 2020, annual box office sales are expected to reach 100 billion yuan, according to industry estimates.
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
3. Deepika Padukone
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
纽约前市长迈克尔·R·布隆伯格(Michael R. Bloomberg)正在为抗击气候变化花费自己私人财产的数千万美元，他在一份声明中说，“全球气温稳步上升、如今破纪录地上升的问题，不是一个未来的问题。这是一个迫在眉睫的明显危险，对经济、健康、环境和地缘政治有重大的危害。”
Antiviral drug discovery: broad-spectrum drugs from nature
The story of the strong V-shaped recovery of the Chinese economy this year was followed by reports of soaring housing prices in many cities.
Vo said with each plane flying 12 to 16 segments a day, one late flight can easily cascade into several delays in a single day. To offset that, the airline’s systems operation and control center makes adjustments when needed. That can involve inserting spare planes and extra crews into the schedule to make sure flights stay on time.
Influenza neuraminidase: A druggable target for natural products
The Belt and Road Initiative: The Silk Road Economic Belt and the 21st-Century Maritime Silk Road
Professor Ivarsflaten cited the U.K. Independence Party, whose official platform focused on Brexit but whose pitch to voters emphasized immigrants’ effects on the economy and culture, as an example of an effective hybrid populist pitch.
Everybody has heard by now that health care companies are promising hunting grounds for job seekers, and the New Year will see hiring perk up elsewhere, too.
在所有这些影片中，斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿，包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
With the Russian rouble depreciating against other major currencies, there has been an increase in visitors to this country in recent years.
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
2. How to write a CV
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
No matter what the inherent method of momentum, all of these engines leverage the latest engine technology to maximize both their power and fuel economy, and run the gamut from the tiny and efficient 1.0-liter turbocharged three-cylinder unit offered in the Ford Fiesta to the Chevrolet Corvette Stingray’s mammoth 6.2-liter V8 that proves there’s no substitute for sheer displacement. We’re featuring Wards’ 10 Best Engines in the accompanying slideshow.
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Lufax, which started four years ago has emerged as the leader due to innovative credit rating techniques.
Andy Murray's US Open victory and Olympic gold medal helped him to become the most searched-for British Olympian.
After rising every year since 2008 global gold supply plateaued last year, according to the World Gold Council. In China, the world’s biggest producer, it fell by a record 9 per cent, the second time output has fallen in the country since 1980.
The report provided in-depth observations on 28 Chinese business and administrative capitals - excluding Beijing and Shanghai - using several indicators.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Inhibition of SARS coronavirus helicase by bismuth complexes
The data showed that Samsung took the top spot, followed by Apple in second place. Even so, the shipments of the two top tech giants declined respectively by 3 percent and 7 percent, demonstrating decreased global market shares.
The Disaster Artist is part buddy movie, part show-business fable, and part behind-the-scenes DVD featurette.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Last year he told an interviewer that 'among others' he would be giving his riches to Choupette.
A minimum of 70 per cent of the con-tent must be delivered online in order for programmes to be eligible for the online ranking. Nine out of the 15 ranked schools had no requirement to study on campus at all. The remaining six schools insisted their students attend weekend or week-long residential classes.
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
We were forced to leave our comfort zone but were rewarded with unique experiences, says one graduate.
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Lenovo CEO Yang Yuanqing
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Yes, pensions for retirees at state and municipal levels are preventing recovery. Corporate pensions are also a big problem, widening America's inequality gap: Drug company McKesson's CEO has been boss for 14 years, but will retire with a $159 million pension, while the income of America's average wage earner has stagnated for 30 years.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
So what forces will shape the questions asked next year? It depends on who (and where) you are. While buyers should brace for another year of high-stakes bidding wars, residents of the city’s far-flung neighborhoods (I’m talking about you, Grand Concourse) should be ready for an onslaught of prospective residents seeking bargains — bargains, that is, relative to the gilded ZIP codes that are out of the reach of most mortals.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
具有荷兰和美国双重国籍的Frans de Waal和另一位美国科学家Jennifer Pokorny获得这一奖项，他们的研究确认黑猩猩可以通过辨认同类的屁股照片来认出不同的个体。
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Another exceptional new field is that of nanotechnology.
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Forbes said that much of the decline in Trump's net worth is due to softness in the midtown Manhattan real estate market.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
The findings of the US and UK scientists are based on thousands of global temperature measurements taken daily on land and at sea.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
French business schools top the 2017 ranking. Edhec Business School, based in Lille and Nice, leads the field for the first time. HEC Paris, which dominated this ranking since its first edition in 2011, drops to second place.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Against: It's not yet managing to win top honors from critics' groups.
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
It is the first time in the rankings’ 19-year history that two schools have between them held the top two spots in both categories.
Even if they played an imperfect game, the Golden State Warriors managed to maintain their perfect start.
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Gunal Youssouf, 23, is a Teach Firster who has joined the UK arm of PwC’s management consultancy graduate scheme. She says the two-year program-me gave her a chance to taste teaching without the cost of studying for a traditional qualification.
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
200911/88512.shtmlA 1936 Nobel Peace Prize discovered at a South American pawn shop has been sold at auction in Baltimore for $1.16 million.
Rihanna vs. Rosario Dawson Both stars wore this long satin Dolce & Gabanna dress in different colors. 蕾哈娜和罗莎里奥·道森都穿了这件款式一致颜色不同的D&G
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
“与前些年相比，今年两会适逢领导人换届，还将讨论机构改革。会上还将讨论贯彻执行十八大政策的详细规划。”Lee Kyu-hyung, Republic of Korea ambassador
That cold was drawn into the interior of the country by a loop in a current called the jet stream that allowed Arctic air to spill southward. But an offsetting kink allowed unusually warm tropical air to settle over the West, large parts of Alaska and much of the Arctic.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
“…said he never lets people see him sweat — but he was sweating profusely.”
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
The world is casting its eye on Brazil for hosting two of the most coveted sporting events — the 2014 FIFA World Cup and the Summer Olympics two years after. Except for watching exciting games and cheering for your favorite team and players, you can also take a trip to “the lungs of the earth”, the Amazon forest, to escape the crowds and embrace nature. Either way, Brazil is sure to leave you with an unforgettable memory.
The full list of this year's honorees follows.
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
4. Will China's one-child policy change in 2010?
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
James Bond is one of the few constants that movie lovers have in this crazy world of ours. We seem to know that, no matter what, a new Bond movie is always on the way.
Sixty-one percent of Chinese college students who graduated in 2014 are satisfied with their current jobs, a survey has revealed.
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
Bobbi's dad Anton, 28, admits that he had his concerns at first, but is now comfortable with Bobbi's routine.
If nothing else, it's clear that when it comes to the summer, the NBA season doesn't really ever stop. It just switches gears.
Length-scale dependence of protein hydration-shell density
Anti-dumping cases were much easier to bring in the US than in the EU where companies first had to pass a public interest test.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
7. Dental hygienist
Call it the crisis of whiteness.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
"To make the world a better place, I invented a transformative water purifier," Google quoted Zhang as saying. "It takes in dirty and polluted water from rivers, lakes and even oceans, then massively transforms the water into clean, safe and sanitary water. When humans and animals drink this water, they will live a healthier life."
The story of the year will be the New York City trial of Khalid Sheik Mohammed.
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