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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

“这可以归结为3个问题:怎样推动平台不断升级,怎样继续强化团队,怎样打造与合作伙伴的一系列联盟,以加速自身成长?”凯斯表示。
One such development is 60 Water Street in Dumbo, a 290-unit rental with a 24-hour concierge and a roof deck offering Manhattan views. Leasing begins next month, with rent for a two-bedroom starting at a jaw-dropping $6,018 a month. “People want that condo-like living, even though they’re renting and not owning,” said Jodi Ann Stasse, the managing director of new developments for Citi Habitats.

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
From the themed collection: 恒生指数报收28224.7点 内房股大跌
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

北京2016年受理外籍人士及其家属永久居留申请较2015年增长426%。
Song “Friends Forever” (Yang Kun and Zhang Liangying)

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
From the themed collection: 瓷砖产品趋向风格多样化、个性化
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

需要注意的是,票房总收入和个人收入是两个不同的概念。在2012年6月到2013年6月期间(这是我们编制最新全球100名人榜所采用的时间段),唐尼的估计个人收入为7,500万美元,比强森多挣2,900万美元。而本文所讨论的数字是每位明星出演的电影在今年斩获的全球票房。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

Wishing you all the blessings of a beautiful New Year season.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

Canadians: I'm afraid that while you are here you will be repeatedly mistaken for Americans and blamed for all sorts of stuff you had nothing to do with. Unless you can think of a quick and simple way to distinguish yourselves at a glance – flower in lapel? Saddle shoes? Maple leaf eyepatch? – then you are just going to have to suck it up.
The relocation is also part of the integration plan for the Beijing-Tianjin-Hebei cluster, which aims to ease congestion in the capital and achieve more balanced development in the region.
你本应该享受生活,不该时时刻刻感到压力。如果你的大部分时间都在为工作的是感到压力很大,说明你没有得到一份好的工作。
These countries performed the best overall in the 2017 Best Countries rankings. The rankings aim to gauge global perceptions of the world’s biggest economies.

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

这名43岁的女子被判处为期12个月的行为考察,并且不得再次拥有宠物。
Industrial production rose 6.1 per cent year on year in October, according to China’s National Bureau of Statistics, unchanged from September’s level and just below a median forecast from economists of 6.2 per cent.
Economists had forecast a 1.5 per cent annual rate, after a 1.6 per cent reading in September. Beijing's inflation target is "around 3 per cent" this year.
羽毛球、篮球、击剑、柔道、乒乓球、跆拳道、网球、举重、摔跤、室内排球、拳击、曲棍球#(&xYyCk,DE@+,qFq。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

写博客有时也很浪费时间。HitTail会分析你的谷歌网站管理员工具里的数据,然后推荐你写一些“热门词”。另外,HitTail还有一个熟练写手组成的网络,可以帮助创建博客内容。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
From the themed collection: 供给侧改革 提速家居行业转型
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

但许多人预测将会出现经济崩盘,他们认为,旷日持久的欧元区危机加上房地产泡沫,将使相当大一部分中国工业失去盈利能力。这将暴露出各种隐藏的金融脆弱性,推动形成一场螺旋式下降。其他人认为,北京方面有充足的资源可以避免一场危机,不过他们指出,由于中国的增长模式依赖于基建和土地出售,且汇率和利率受到僵硬控制,它也许并没有所有必要工具。

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

['?bs?lu:tli]
n. 诱惑,引诱

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
From the themed collection: 智能家居缺乏统一标准成发展瓶颈
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

补救办法: 做预算。 如果你不能估算需要多少钱才能过上令你感到舒适的生活,你就无法确切地知道为了1万美元薪水而换工作是否真的划算。在比较新、旧工作时,列出各自的优缺点,这会对你很有帮助。如果新工作只是薪水更高一点,那么你可以比较下这个工作是否要求更长的工作时间和完成更多的工作任务。请记住,调查表明:年收入在7.5万美元以内,幸福感会随着薪水的增加而增加,但是一旦薪水超过这个水平,幸福感的增加便不再明显。因此,如果你认为薪水增加到8.5万或9万美元会使你更加快乐,这时你或许应该着手解决生活中那些与金钱无关而引起的不快乐。
清华大学在计算机科学和工程学两个学科中排名居首。这所中国院校今年取代了麻省理工学院,成为计算机科学最强学府。

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

艾伦非常有才,主持也自然,她知道如何调动世界范围内的观众的心绪。她是奥斯卡的铁杆粉丝,而我们也是她的庞大粉丝团。真是完美的契合。
While the president emerged as the narrow winner on the night, the encounter, which was cordial and largely uneventful compared with the previous two debates, is unlikely to have much impact on the outcome of the election.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

n. 信用,荣誉,贷款,学分,赞扬,赊欠,贷方
con全部+tin拿住+uous→连续不断的
In the original casting, Michael Keaton was set to play the character. However, ABC executives begged the writers and producers to keep Jack alive. They believed the character was too likeable to die off so quickly. The writers agreed. Michael Keaton was not interested in signing up for a long-running show. Instead, the role of Jack was given to Matthew Fox. The rest is TV history.
By 2020, annual box office sales are expected to reach 100 billion yuan, according to industry estimates.

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

反对:《至暗时刻》目前还没有被一所影评机构评为最佳电影。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
From the themed collection: 民宿何时不再被“民诉”
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

Lecent Ross枪击案已逮捕两人
卓越雇主排名:7

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

3. Deepika Padukone

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

纽约前市长迈克尔·R·布隆伯格(Michael R. Bloomberg)正在为抗击气候变化花费自己私人财产的数千万美元,他在一份声明中说,“全球气温稳步上升、如今破纪录地上升的问题,不是一个未来的问题。这是一个迫在眉睫的明显危险,对经济、健康、环境和地缘政治有重大的危害。”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

紧随Fitbit和谷歌眼镜(Google Glass)之后,许多公司开始蜂拥进入这一市场,带来了许多装有感应器的臂章、服饰以及眼镜。这个领域现在炙手可热,但最早使用这些设备的人们似乎都在等待那个时刻,让他们不再显得特立独行。(你知道的,谷歌眼镜的粉丝们现在有了个专门的贬义称呼“Glasshole”。)
The story of the strong V-shaped recovery of the Chinese economy this year was followed by reports of soaring housing prices in many cities.
Vo said with each plane flying 12 to 16 segments a day, one late flight can easily cascade into several delays in a single day. To offset that, the airline’s systems operation and control center makes adjustments when needed. That can involve inserting spare planes and extra crews into the schedule to make sure flights stay on time.
课程安排:为期一周的课前培训后,学员在每周末的星期五和星期六交替上课,周五晚提供住宿。最后一个学期需住校学习两周,其余时间在线完成学习任务。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

The Belt and Road Initiative: The Silk Road Economic Belt and the 21st-Century Maritime Silk Road
Professor Ivarsflaten cited the U.K. Independence Party, whose official platform focused on Brexit but whose pitch to voters emphasized immigrants’ effects on the economy and culture, as an example of an effective hybrid populist pitch.
Everybody has heard by now that health care companies are promising hunting grounds for job seekers, and the New Year will see hiring perk up elsewhere, too.
在所有这些影片中,斯文顿用的是同一个牙齿设计专家——伦敦Fangs F/X公司的克里斯·莱昂斯(Chris Lyons)。他在工作中设计了各种牙齿,包括为坎耶·韦斯特(Kanye West)一个音乐录影带中的一只杜宾犬设计了金色尖牙。
n. 毂,木片,中心

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

组建或加入一个学习小组
With the Russian rouble depreciating against other major currencies, there has been an increase in visitors to this country in recent years.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Critical Review

The role of biosensors in the detection of emerging infectious diseases

人社部下属的社会保障研究所的所长金维刚称,鉴于居民消费价格指数低于预期、工资和GDP涨幅也有所放缓,所以今年上调5.5%这一数字是合理的。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

2. How to write a CV

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

No matter what the inherent method of momentum, all of these engines leverage the latest engine technology to maximize both their power and fuel economy, and run the gamut from the tiny and efficient 1.0-liter turbocharged three-cylinder unit offered in the Ford Fiesta to the Chevrolet Corvette Stingray’s mammoth 6.2-liter V8 that proves there’s no substitute for sheer displacement. We’re featuring Wards’ 10 Best Engines in the accompanying slideshow.
这家总部位于亚特兰大的集团预测,经并购、资产剥离和汇率波动调整,今年销售额将增长3%,而之前的预期为4%至5%。
奥巴马取得胜利,也以为着在接下来四年的发展道路:关于国家开支、税收、医疗健康、政府的角色,还有应对中国发展和伊朗核问题等的外交措施。
2011年,在《老友记》最后一季播出7年之后,美国卫星电视频道Comedy Central再次播放该剧,观看人数超过了3600万,而观众的年龄主要分布在16岁至34岁之间。假期时,看剧人数更是由于播放集数增加而飙升。

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Lufax, which started four years ago has emerged as the leader due to innovative credit rating techniques.
Andy Murray's US Open victory and Olympic gold medal helped him to become the most searched-for British Olympian.
After rising every year since 2008 global gold supply plateaued last year, according to the World Gold Council. In China, the world’s biggest producer, it fell by a record 9 per cent, the second time output has fallen in the country since 1980.
The report provided in-depth observations on 28 Chinese business and administrative capitals - excluding Beijing and Shanghai - using several indicators.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

《三生三世十里桃花》的豆瓣评分为6.4分,一些网友认为,这部剧的爱情戏码太多了。
“环境越来越受到政策制定者的重视。”世界黄金协会市场情报部门负责人阿利斯泰尔?休伊特(Alistair Hewitt)说,“黄金开采受到更严格的监管。”

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

The data showed that Samsung took the top spot, followed by Apple in second place. Even so, the shipments of the two top tech giants declined respectively by 3 percent and 7 percent, demonstrating decreased global market shares.
Eleven James:
对于一种色彩潮流(又或说两种色彩潮流)而言,要包含的和不同话题有关的信息传递太多了,但潘通在声明中称,体现社会潮流并用一种颜色捕捉它们,是公司的工作。和往常一样,这种颜色将会进入我们生活中使用的面料。
1.Deadpool
The Disaster Artist is part buddy movie, part show-business fable, and part behind-the-scenes DVD featurette.

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 建材以旧换新撬动150亿元潜在商机
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Last year he told an interviewer that 'among others' he would be giving his riches to Choupette.
Until Dawn
A minimum of 70 per cent of the con-tent must be delivered online in order for programmes to be eligible for the online ranking. Nine out of the 15 ranked schools had no requirement to study on campus at all. The remaining six schools insisted their students attend weekend or week-long residential classes.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

马特达蒙凭借他在《火星救援》中扮演的被困宇航员一角而荣获喜剧类最佳男主角奖项。
6. 2012年搞笑诺贝尔奖之文学奖

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 保温材料行业走向绿色是必然趋势
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

We were forced to leave our comfort zone but were rewarded with unique experiences, says one graduate.
幸存的那只猫咪被命名特鲁珀,目前已经康复并找到了一个新家。
伊莎贝拉卡敏斯卡(Izabella Kaminska)

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Plum Alley:
Age: 39
厌倦了一成不变的生活?何不去探险,让身心重新焕发活力?毫无疑问,南极洲会是个好去处。亲眼目睹企鹅嬉戏,成群结队的海鸟飞过天空,要比观看电视纪录片更令人兴奋。想象一下,置身于雄伟冰山和原生态山脉构成的世界中,是多么刺激和美好的一件事啊!但要注意的是,南极洲地处极地,因此行前要做好充足准备。保暖靴、防寒外套、手套、羊毛袜和帽子一样都不能少。

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
From the themed collection: 谁推高了三四线城市的房价?
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 2014红棉奖建材产品成最大赢家
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Lenovo CEO Yang Yuanqing

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

Yes, pensions for retirees at state and municipal levels are preventing recovery. Corporate pensions are also a big problem, widening America's inequality gap: Drug company McKesson's CEO has been boss for 14 years, but will retire with a $159 million pension, while the income of America's average wage earner has stagnated for 30 years.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

So what forces will shape the questions asked next year? It depends on who (and where) you are. While buyers should brace for another year of high-stakes bidding wars, residents of the city’s far-flung neighborhoods (I’m talking about you, Grand Concourse) should be ready for an onslaught of prospective residents seeking bargains — bargains, that is, relative to the gilded ZIP codes that are out of the reach of most mortals.
请接受我节日的祝贺。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

200912/93010.shtml
['staili?]
人社部下属的社会保障研究所的所长金维刚称,鉴于居民消费价格指数低于预期、工资和GDP涨幅也有所放缓,所以今年上调5.5%这一数字是合理的。
bacteria

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
From the themed collection: 哈尔滨市重拳治理商品房市场乱象
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

比利时和乌拉圭这两个袖珍之国因为包容性最大限度地增强了自己的实力,巴西、阿根廷、西班牙和德国这四个本届杯赛的夺冠大热门肯定会对他们特别小心。他们将会是有力的提醒,告诉世界小国家通常也能一击致命,就像巴西本土的小动物蚊子和蝎子一样。
具有荷兰和美国双重国籍的Frans de Waal和另一位美国科学家Jennifer Pokorny获得这一奖项,他们的研究确认黑猩猩可以通过辨认同类的屁股照片来认出不同的个体。

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

Another exceptional new field is that of nanotechnology.
只跟那些能凸显你聪明的人做朋友,哪怕他们觉得你坏坏哒。

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

1. 2012年搞笑诺贝尔奖之心理学奖

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

Forbes said that much of the decline in Trump's net worth is due to softness in the midtown Manhattan real estate market.
答:其实我并不怎么关心作品火不火的,就是专注于自己的作品而已。每次我关注的就是要怎样用最好地推进剧情而已。我关注的是行为和故事,不是受欢迎程度。
清华大学位列第45名,是亚洲排名第三的高校。北京大学位居第57位。浙江大学排名第67位,本次是该校首次跻身该榜单100强。
adj. 青春期的,青少年的

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
From the themed collection: 海南全面停办产权式酒店用地审批
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

n. 示范,实证,表达,集会
The findings of the US and UK scientists are based on thousands of global temperature measurements taken daily on land and at sea.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

达奇斯说:阿迪达斯在今年的12个月里增加了3400万名新粉丝。公司把粉丝们带动了起来,粉丝们一整年都在进行积极的讨论,公司因而从中受益。
French business schools top the 2017 ranking. Edhec Business School, based in Lille and Nice, leads the field for the first time. HEC Paris, which dominated this ranking since its first edition in 2011, drops to second place.
时间:2011-12-28 编辑:Richard

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

Against: It's not yet managing to win top honors from critics' groups.
n. 紧张,压力
单词movement 联想记忆:

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

It is the first time in the rankings’ 19-year history that two schools have between them held the top two spots in both categories.
Even if they played an imperfect game, the Golden State Warriors managed to maintain their perfect start.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

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Gunal Youssouf, 23, is a Teach Firster who has joined the UK arm of PwC’s management consultancy graduate scheme. She says the two-year program-me gave her a chance to taste teaching without the cost of studying for a traditional qualification.
经济学家的预期中值为同比上涨0.9%。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

entertainment
3.你必须支持我所支持的队伍。

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

200911/88512.shtmlA 1936 Nobel Peace Prize discovered at a South American pawn shop has been sold at auction in Baltimore for $1.16 million.
Rihanna vs. Rosario Dawson Both stars wore this long satin Dolce & Gabanna dress in different colors.   蕾哈娜和罗莎里奥·道森都穿了这件款式一致颜色不同的D&G
英国

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

n. 运输,运输系统,运输工具

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

“与前些年相比,今年两会适逢领导人换届,还将讨论机构改革。会上还将讨论贯彻执行十八大政策的详细规划。”Lee Kyu-hyung, Republic of Korea ambassador
That cold was drawn into the interior of the country by a loop in a current called the jet stream that allowed Arctic air to spill southward. But an offsetting kink allowed unusually warm tropical air to settle over the West, large parts of Alaska and much of the Arctic.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
From the themed collection: 涂料企业做微信营销的4个理由
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

“…said he never lets people see him sweat — but he was sweating profusely.”
不过,对韩国和东盟(Asean)国家的出口都下滑了约3%,而对香港的转口贸易下滑幅度逾16%。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
From the themed collection: 海洋王照明监事崔彤进行书面辞职
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

国家统计局表示,这一比例虽然与经济合作与发展组织成员国2.4%的平均水平还有差距,但已超过欧盟2.08%的平均水平。
Spider-Man: Homecoming

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

数百所国内高校的2017届、2015届和2013届毕业生、共281万人参与了这项调查。
你永远都不能把一只狼变成宠物狗。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

扫盲:Illuminati字面意思为“先觉者”,是启蒙运动时期的一个巴伐利亚秘密组织,成立于1776年5月1日。它的成员中包括文学巨匠歌德和哲学家海德这样声名赫赫的人物,但它存在的时间却十分短暂。我们熟知的Illuminati(光明会)最早的首脑,正是大名鼎鼎的伽利略。他非常喜爱对称物,于是另一位光照派成员——艺术大师贝尔尼尼便为伽利略设计了一件杰作。他将16世纪时人们认为组成世界的四大元素:土(earth)、水(water)、火(fire)、气(air)以及Illuminati(光明会)这五个原本并非对称字的单词设计成了对称的文字,即在倒转180度之后与原来的形状一模一样的文字图案。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

福布斯杂志认为,特朗普净资产的下降,主要是由于曼哈顿市中心房地产市场的疲软。
Consider:
早先一个由活动分子和美国人权基金在一月份投放100000份电影的计划被推迟到了上个月的新年后。
Jude Webber

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

201001/94005.shtml

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

The world is casting its eye on Brazil for hosting two of the most coveted sporting events — the 2014 FIFA World Cup and the Summer Olympics two years after. Except for watching exciting games and cheering for your favorite team and players, you can also take a trip to “the lungs of the earth”, the Amazon forest, to escape the crowds and embrace nature. Either way, Brazil is sure to leave you with an unforgettable memory.
奥巴马将迎来第二个任期,摆在他面前的任务依然很艰巨:如何处理1万亿美元的高额年度财政赤字,如何削减高达16万亿美元的国债,如何改革开支高昂的社会事业,如何应对党派斗争激烈陷入僵局的美国国会等等。
The full list of this year's honorees follows.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
From the themed collection: 世园会三大主场馆年底封顶
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

4. Will China's one-child policy change in 2010?
不过,对韩国和东盟(Asean)国家的出口都下滑了约3%,而对香港的转口贸易下滑幅度逾16%。

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

James Bond is one of the few constants that movie lovers have in this crazy world of ours. We seem to know that, no matter what, a new Bond movie is always on the way.
Sixty-one percent of Chinese college students who graduated in 2014 are satisfied with their current jobs, a survey has revealed.

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 明年房地产市场将降温
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

下面是消费者和投资者在2015年也许可以期盼的5个好消息。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

Bobbi's dad Anton, 28, admits that he had his concerns at first, but is now comfortable with Bobbi's routine.
vt. 转移,分心
If nothing else, it's clear that when it comes to the summer, the NBA season doesn't really ever stop. It just switches gears.

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Anti-dumping cases were much easier to bring in the US than in the EU where companies first had to pass a public interest test.
10.Selfie Sticks
单词compromise 联想记忆:
优秀老板看起来都会拥有的一个关键是:他们都是解决问题的高手。他们不仅能够发现问题,并能头脑风暴出成功创新的方法来解决问题。

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 环保风暴过后 三亚6项目整改
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

7. Dental hygienist
Call it the crisis of whiteness.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

"To make the world a better place, I invented a transformative water purifier," Google quoted Zhang as saying. "It takes in dirty and polluted water from rivers, lakes and even oceans, then massively transforms the water into clean, safe and sanitary water. When humans and animals drink this water, they will live a healthier life."
The story of the year will be the New York City trial of Khalid Sheik Mohammed.
adj. 创造性的

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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欧盟完成与墨西哥现有贸易协议的(重新)谈判也是如此。在与墨西哥签订协议上,布鲁塞尔很可能比特朗普先冲过终点线。
无论是左翼还是右翼,他们都标榜自己是反精英的大众代表和不合适的局外人,并作为魅力领导人与追随者密切联系,他们往往通过弥天大谎来操纵这种联系,用以谋求自己的进步;他们威胁既有的行为准则和约束性制度,把这些准则和制度描述为他们所代表的民意的敌人。

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